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Oxidative stress has been identified as having an important role in cerebrovascular disease and given increasing recognition of the overlap between vascular dementia and AD (mixed dementia) and the contribution of vascular changes to AD [93] investigating potential effects of cerebrovascular disease as a covariate would be an important direction for future studies
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Due to their lower ionization energies and higher ultraviolet molar absorption coefficients, these matrices facilitate the efficient generation of radical molecular cations in MALDI
NICE guidelines (NG100) recommend early referral to a rheumatology specialist for anyone with suspected persistent synovitis, particularly if multiple small joints are affected or if there is morning stiffness lasting more than 30 minutes
Interestingly, Increasing the bio-availability of N-3 PUFAs [14], but not enriching the diet with a combination of micronutrients [15] early in life protected against the ES-induced reduction in neuronal survival
At microdose levels, sleep effects are typically neutral
