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The additional pathway would be the direct modulatory effects microbes and metabolites have on the BBB itself, influencing the integrity of the brains primary defense mechanism and therefore impacting brain health

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This medicine kills or stops the growth of bacteria causing the infection

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In addition, in both the acute phase and Long COVID, a single latent vector could be derived from these somatic and affective symptoms, demonstrating that these symptom profiles are the expression of a shared core, namely the acute COVID-19 and Long COVID neuropsychiatric symptoms [25, 26]