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"New chemical entities", that is, synthetic molecules that the human body has never been previously exposed to in our history

It is therefore likely that GSTP-silencing may directly elicit mitochondrial dysfunction, resulting in the rapid generation of ROS, which is reasonable because the primary source of ROS is mitochondria

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Its natural origin, ability to cross the blood-brain barrier, and multi-modal mechanismsimpacting oxidative stress, mitochondrial dysfunction, and immune dysregulationmake it a promising candidate for integrative treatment approaches

While n-3 PUFAs have been associated with immunomodulation and antioxidant activity, glutathione is recognized as one of the main pillars of the endogenous antioxidant defense system

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