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doi: 10.1053/j.gastro.2021.02.060 13

Final Results of NRG Oncology RTOG 0246: An Organ Preserving Selective Resection Strategy in Esophageal Cancer Patients Treated with Definitive Chemoradiatio

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For example, E50K mutated OPTN induced impairment of autophagy that led to cell death in RGC-5 cell lines 28 , and rapamycin, an autophagic inducer, protected RGCs in E50K OPTN overexpressed rats in vivo 29

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Neuronal neurotransmitter equilibrium relies on this cycle which concurrently facilitates nitrogen metabolism in non-neuronal tissues