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Chan HL, Chan CK, Hui AJ, Chan S, Poordad F, Chang TT, Mathurin P, Flaherty JF, Lin L, Corsa A, Gaggar A, Subramanian GM, McHutchison JG, Lau G, Lee S, Gane EJ

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Pycnogenol acts as a potent scavenger of both hydroxyl and superoxide radicals, neutralizing them before they can inflict cellular damage

Electrostatic interactions between an acidic region near the N-terminus (Asp1257-Asp1260) and basic residues Lys1266 and Lys1269 in the C-terminal half are the most likely drivers for these long-range transient contacts

Even though oral supplements can be effective for many people, the absorption rate may vary and be lower than vitamin B12 shots

Appl Microbiol Biotechnol 24:375378 Watanabe K, Kato N, Yoshida N (1989) Glutathione, its manufacture with yeast, and the effects of complex amino acids in medium