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Unopened, refrigerated Unopened Mounjaro and Zepbound pens have a manufacturer-assigned expiration date, typically 12 to 18 months from the date of manufacture

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NRF2 is directly phosphorylated by protein kinase R-like ER kinase (PERK), a key mediator of the NRF2-HO-1 signaling pathway activation in response to erastin

10.1001/jama.2018.3024 61 ZhuJ.YuX.ZhengY.LiJ.WangY.LinY.et al (2020)

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