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The lack of anti-atherosclerotic and plaque-stabilizing effects of incretin-based medications might contribute to elevated cardiovascular risk, especially acutely following their discontinuation

The New England journal of medicine, 384(11), 9891002

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Furthermore, the evidence base for the mechanisms possibly involved in the mood-regulating properties of these medications appear more tentative and would benefit from a more in-depth assessment

Triglyceride levels 10 mmol/L or suspected familial hypercholesterolaemia require urgent medical attention or specialist referral