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Side effects are possible

Lower-dose protocols may allow for longer-term use with fewer side effects, which matters because inflammation-driven damage accumulates slowly over time

CVD Trials Type 2 diabetes mellitus (T2DM), obesity, dyslipidemia, and hypertension are major players in the development of cardiovascular disease (CVD)

A separate 2024 analysis in Frontiers in Endocrinology showed that 0.5 mg weekly led to sustained weight loss and metabolic improvements over 12 months in patients with type 2 diabetes

Regular, on-schedule dosing combined with appropriate nutrition , adequate protein intake , and physical activity produces the best outcomes