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Richmond, BC, Canada, and cultured in Complete Medium (Meisen CTCC, Zhejiang, China) in an incubator (3111

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An important consideration with respect to the ability of GSHee to prevent the deleterious effects of fentanyl on breathing was that the opioid appeared to elicit its full sedative effects in the presence of the GSHee (e.g., righting-reflex times and general observations of behavior could not discriminate between the effects of fentanyl in vehicle-treated or GSHee-treated rats)