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4,5 The FDA approval of Wegovy was based on the results of the STEP ( S emaglutide Tr eatment E ffect in P eople with Obesity) clinical trial program, which included four phase 3a clinical trials involving approximately 4,500 patients

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The search was limited to outcome trials evaluating the efficacy of DPP-4 inhibitors, GLP-1RA and SGLT-2 inhibitors on cardiovascular, heart failure or renal outcomes in adult patients with or without type 2 diabetes

Zhou D, Liang Q, Ge X, Xu J

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