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That compounds to roughly 8 pounds per year of additional weight loss driven purely by metabolic rate changes, separate from the appetite effects

Clinical efficacies, underlying mechanisms and molecular targets of Chinese medicines for diabetic nephropathy treatment and management

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Its consequences can be severe, ranging from heart attacks and strokes to nerve damage and vision loss 1

Future investigation with prolonged treatment duration and increased dosages will further elucidate whether there are any direct modulating effects of tirzepatide on NAFLD/NASH progression.

Age and Obesity Factors Age is another important factor, as patients over 50 years old are more likely to develop ischemic optic neuropathy