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Cagrilintide acts on amylin receptors in the hindbrain to suppress appetite, slow gastric emptying, and reduce postprandial glucagon secretion

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The peptide is associated with changes in the hypothalamic-pituitary-adrenal axis, and this may play role in suicidal patients with major depressive disorder with altered DSIP-like immunoreactivity levels

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doi: 10.1016/s0169-409x(02)00021-2 122 GaoYJoshiMZhaoZMitragotriS

For long-term studies or to prevent degradation from repeated freeze-thaw cycles, it is best practice to aliquot the freshly reconstituted solution into single-use volumes and store them frozen at -20C or colder