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The most recent is a 2016 meta-analysis of sixteen trials that found that selenium supplementation reduced serum TPO-antibodies levels after 3, 6 and 12 months in a population with chronic autoimmune thyroiditis treated with L-T4 ( Reference Wichman, Bonnema and Hegedus 88 )

This has led to suggestions that excessive folic acid supplementation could, under certain circumstances, induce a functional folate deficiency

These bacteria, residing in a glycan-rich environment, are able to digest mucus through mucus-degrading enzymes, such as sulphatase, glycosidase, neuraminidase, galactosidase, cysteine protease, and sialidases that cleave the mucus, producing short-chain fatty acids (SCFAs)

Yeo TW, Weinberg JB, Lampah DA, Kenangalem E, Bush P, Chen Y, Price RN, Young S, Zhang HY, Millington D, Granger DL, Anstey NM

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Recent research on the gut-kidney axis has revealed novel therapeutic pathways to alleviate inflammation, renal injury, and uremia, thereby preventing adverse clinical outcomes in CKD ( Figure 2 )