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These drugs mimic natural gut hormones to slow digestion, reduce appetite, and improve blood sugar control

Standard diabetes and weight management monitoring should continue as per NICE guidance, including HbA1c measurement, cardiovascular risk assessment, and monitoring for common GLP-1 adverse effects such as gastrointestinal symptoms

Unaffected individuals from both cohorts obtained from Kahemba were not considered to have konzo at the time of sampling following the 3 main criteria for diagnosis outlined by the World Health Organization

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When appropriate, 100 g/ml kanamycin or 15 g/ml oxytetracycline was used for selection