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[8] The honest framing for both is that these are surrogate endpoints body weight, HbA1c, liver fat measured over trial-length horizons

Studies have shown the role of serum GGT as a surrogate of oxidative stress 26,27,28 and pointed out that both SUA and GGT are markers of cardio-metabolic risk 28,29,30,31,32

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Weight loss drugs Appetite suppressants and GLP-1 drugs have become more popular and often show quick results

Signal 9 , 11 (2011)