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These findings suggest that the effects of SGLT2 inhibitors extend beyond hemodynamic improvements, involving direct modulation of intracellular pathways implicated in kidney injury

This is why food quality becomes even more important

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Four years later, the RECORD was published, which trial enrolled 4,447 patients with uncontrolled T2DM on maximum tolerated monotherapy for at least 2 months and assigned them to rosiglitazone versus sulfonylurea or metformin

At the same time, there are potential downsides with these medications, such as high cost, side effects, and questions about long-term use

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