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Metoclopramide, an FDA-approved prokinetic for gastroparesis, carries a boxed warning for tardive dyskinesia and should generally be limited to 12 weeks or less of therapy

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In the PD model, DR-AB, an antibody that targets the DR region of the NKA- subunit, disrupts the cytoplasmic interaction between NKA-1 and Parkin, promotes Parkin translocation to mitochondria, and enhances mitochondrial autophagy

Bremelanotide's prescribing information includes a warning about transient blood pressure increases