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Angiotensin IIInduced Reactive Oxygen Species and the Kidney

All pharmacokinetic data cited here comes from the published Phase 2 trial

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16.3 Dosing Considerations in Pediatric Populations Dosing must be individualized

Its four-residue sequence alanine, glutamic acid, aspartic acid, and glycine gives it two acidic side chains, making the molecule negatively charged at physiological pH

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