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Additionally, elevated histone-bound DNA content, a hallmark of apoptosis, was observed (Fig

Diabetes Care 35 , 717722 (2012)

additionally, patients included in the database may not have been fully representative of all patients in the UK and Germany

It is conceivable that some forms of renal disease could differentially affect glomerular filtration rate and tubular reabsorption resulting in a clearance of topiramate not predicted by creatinine clearance

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