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Genetic predisposition to weight regain, influenced by variants in appetite-regulating genes like GLP1R and MC4R, also affects individual trajectories

Smith EP, An Z, Wagner C, et al

Moreover, this treatment has proven to be safe in adults not suffering from GHD when administered in physiological doses

GILBERT: Yeah

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This included 28,430 cardiovascular deaths (103 per 100,000 person-years), 83,489 nonfatal myocardial infarctions (303 per 100,000 person-years), and 24,521 nonfatal strokes (89 per 100,000 person-years), with a number needed to treat (NNT) of 55 for MACE