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As eating signals feed back into these circuits, they can become less responsive to food and other everyday rewards

2004 May;134(5):1145-51

Other mushroom-derived compounds, including triterpenoids and sterols, also show potent anticancer properties

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Clinical trials have demonstrated substantial weight losswith SURMOUNT obesity trials showing 1522% of body weight reduction at higher doses, while more modest losses were observed in type 2 diabetes trials