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Clinical studies indicate 1-3% concentrations deliver optimal efficacy for skin remodeling benefits without irritation

The method of any one of embodiments 79-142, wherein the therapeutic agent is released from the formulation over a period of at least 7 days

PLGA nanoparticles containing vitamin D3 analogues have demonstrated enhanced treatment effectiveness and decreased systemic absorption in animal models of psoriasis (74)

Chikazumi S (2019) Phys Magn 145:260

The specific signalling outcome is determined by the repressors function

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