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In the human body, ergothioneine occurs in the highest concentration in the erythrocytes, kidneys, liver, eyes, and semen [106]

Interestingly, defects in mitochondrial energy metabolism are also present in the brains of patients with AD, leading to neuronal apoptosis and A deposition, which increases ROS production by interfering with mitochondrial calcium homeostasis and ETC function

It generates hypotheses rather than mechanisms, which suits a compound in this position

Choi HR, Kang YA, Ryoo SJ, et al

Calibrate your goals, stop when your plan says to stop, and treat demo tests as scouting missions for the real thing

Abundant research shows that supplementation with glutathione or its precursors (e.g N-acetyl cysteine) is especially useful in offsetting neurological aging[10]