Because water-soluble medications cannot penetrate the skin via conventional patches, innovations like microneedle transdermal systems would be needed to adapt existing GLP-1s to patches," says Dr
This structural modification has been applied to exenatide, lixisenatide, semaglutide, dulaglutide and albiglutide
The potential antidepressant effect of antidiabetic agents: new insights from a pharmacovigilance study based on data from the reporting system databases FAERS and VigiBase
This may be further pronounced in patients with diabetes with compromised gastrointestinal function due to autonomic neuropathy
Researchers think that this involves the vagus nerve .[ref] Vagus nerve interaction: A 2026 study showed that the GLP-1 receptor is expressed in the nodose neurons, which are the sensory cells that transmit information from the internal organs to the brainstem.[ref] GLP-1 Medications: Semaglutide, Tirzepatide, and Retatrutide Given GLP-1s powerful effects on appetite and glucose regulation, researchers developed synthetic medications that mimic its action
Whether youre managing type 2 diabetes or struggling with weight loss, you may have heard of medications like Ozempic, Wegovy, or Mounjaro
