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15), which dictates the balance between dephosphorylation and phosphorylation, and c , the cellular level of -arrestin, are the two key parameters that determine the dose-response behavior

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The researchers showed that FOXO4-DRI treatment induced apoptosis specifically in senescent chondrocytes while sparing healthy proliferating cells, confirming the selectivity mechanism described in the original Baar et al

To view a copy of this license, visit About this article Cite this article Tiano, J., Tate, C., Yang, B

Siebert, C.V