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SAR441255 demonstrated superior weight loss compared to dual GLP-1/GCG agonists in animal models and did not exhibit major cardiovascular adverse effects in lean monkeys

2023 Sep 11;64(6):453-459

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Effective substances and molecular mechanisms guided by network pharmacology: An example study of Scrophulariae Radix treatment of hyperthyroidism and thyroid hormone-induced liver and kidney injuries

The offer followed shortly after Metsera struck a deal to sell itself to Novos rival, Pfizer, that was worth up to $7.3 billion (which Metsera can still get out of)

The peptide is used in conjunction with a PDE-5 inhibitor