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Tophi: In advanced cases, uric acid crystals can accumulate beneath the skin, forming small, chalky lumps called tophi

Regulation of circadian rhythms through pineal gland affecting melatonin production (melatonin has retinal protective properties)

The cardiovascular benefits of GLP-1RAs are well-established, with clinical trials demonstrating reductions in major adverse cardiovascular events (MACE), improved endothelial function, and lower blood pressure

Dyspepsia: 11% of patients in the Wegovy group compared to 3% in the placebo group

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