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Although some AAV serotypes such as AAV1, AAV2, AAV5, and AAV8 can transduce neurons, they are unable to effectively cross the BBB through non-invasive intravenous injection [155]

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In some cases, regular injections are recommended for lasting benefits, with results lasting about a month between sessions

mansoni (lower pathway), TrxR and GR are replaced with a unique oxidoreductase flavoenzyme, TGR, which provides reducing equivalents for Trx-, GSH- and Grx-dependent reactions

28.) Jenke, D

doi: 10.3389/fphar.2020.591836