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Additionally, thiols are chemically reactive and prone to oxidation, particularly in aqueous and oxygenated environments, leading to the formation of various oxidation products, including disulfides (which may be inactive), such as in the case of NAC (Primas et al., 2023

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TET1 , the founding member of TET family, has been identified as an oncogene in multiple cancers 19,21,25,26,27

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While gentle introduction is wise, some skin types can handle moderate concentrations from the start and don't benefit from extended time at minimal levels