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Some research has explored GLP-1 receptor agonists in neurodegenerative conditions such as Parkinson's disease and Alzheimer's disease, with mixed early findings that cannot be generalised to ADHD

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Some protocols use a 'loading' phase (higher dose for 35 days) followed by maintenance dosing (lower dose long-term), based on the hypothesis that initial synaptogenesis requires stronger signaling, while maintaining new synapses requires less