"Someone with a resting heart rate of 50 bpm, a high HRV, and years of training experience is often highly attuned to subtle changes in their physiology," Grosicki told me
NICE recommends disease-modifying antirheumatic drugs (DMARDs) such as methotrexate as first-line treatment, with biologic therapies (TNF inhibitors, IL-6 inhibitors) or JAK inhibitors for patients with inadequate response
On GLP-1 medications, which suppress your appetite, hitting the right protein target helps ensure that most of the weight you lose comes primarily from fat
doi: 10.2337/db17-0480
Scientists are now investigating whether GLP-1 drugs could help treat substance use disorders, which also involve dopamine-driven reward pathways
Crucially, the review pointed out that GLP1RAs tended to have fewer psychiatric side effects, such as mood swings or addictive potential, than several other current drugs for binge eating