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There is an active debate about whether rapamycin and other rapalogs can extend human healthspan and lifespan

Community reports vary widely, which is itself a signal that responses are individual

51 IGB decreased the incidence of metabolic syndrome from 34.8% (pre-IGB) to 11.6% at 12 months post-IGB removal

It could be argued that doses higher than those used to treat hyperglycemia may be more effective