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Fu X, et al

[15] [1] Those experiencing gastrointestinal side effects from GLP-1 therapy (nausea, vomiting, diarrhoea) should exercise caution with allulose, as additive effects on gut symptoms are theoretically possible

These ROS oxidize PUFAs in cell membranes into lipid peroxides (PUFA-OOH), thereby destroying cell membrane structural stability, attacking cellular DNA and proteins, and causing ferroptosis