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Pursuant to the Loan and Security Agreement, K2HV may elect to convert up to $ In connection with the Loan and Security Agreement, on July 28, 2020, the Company issued K2HV a warrant to purchase up to F-19 The total principal amount of the loan under the Amended Loan and Security Agreement outstanding at December 31, 2023, including the $ Upon the occurrence of an Event of Default (as defined in the Loan and Security Agreement), and during the continuance of an Event of Default, the applicable rate of interest, described above, will be increased by The total debt discount related to the Amended Loan and Security Agreement of approximately $ The net carrying amounts of the liability components consists of the following: The following table summarizes the future principal payments, including the $ Accrued expenses consisted of the following: No provision or benefit for federal or state income taxes has been recorded, as the Company has incurred a net loss for all of the periods presented, and the Company has provided a full valuation allowance against its deferred tax assets

The molecule carries one structural distinction from the native parent: a trans-3-hexenoic acid moiety amide-coupled to the -amine of N-terminal Tyr1