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Its stability characteristics allow for extended observation periods, making it suitable for longitudinal assay designs and comparative analysis studies
There is either increased accumulation of senescent cells or decreased clearance due to weakened immune system in aging individual
Another aspect of slowing disease progression of ALS could be through protection of the BBB, but this warrants further investigation
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5,145 Many recently identified genes, including (human clinical study) the aldose reductase (AKR1B1) gene, VEGF,5,10, methylenetetrahydrofolate reductase (MTHFR) enzyme variants, APOE, and angiotensin-converting enzyme (ACE) genes, play important roles in the polyol pathway, vascular endothelial cell value-addition, and oxidative stress in endothelial cells induced by hyperhomocysteinemia
