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570 Eriodictyol markedly improves cognitive deficits in APP/PS1 mice and inhibits tau phosphorylation and A aggregation in the brain of APP/PS1 mice, which may be related to the activation of the Nrf2/HO-1 signaling pathway to inhibit ferroptosis
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Different concentrations of CA7S, however, were unable to activate endogenous FXR in human intestinal Caco-2 cells, suggesting that CA7S may induce TGR5 expression through an independent FXR mechanism [99]
People who were 65 years and older participating in the trial and using tirzepatide saw their HbA1c drop by around 1.97% to 2.10% regardless of their dose