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Combined with lifestyle therapy in adolescents, phentermine led to significantly greater body-weight and BMI reductions than lifestyle therapy alone at 1 month (1.4 kg, 1.6%), 3 months (2.6 kg, 2.9%), and 6 months (3.2 kg, 4.1%) [56]

However, for some GLP-1 RAs, caution is needed while using them in patients with renal impairment

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As a result, glucose reabsorption may be increased by 20% in individuals with poorly controlled diabetes

2025, doi: 10.14309/ajg.0000000000003760