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Tolerability and Safety Common side effects of popular GLP-1 medications are usually transient and can include: Nausea Diarrhea Constipation Early satiety Gastrointestinal upset during dose escalation Hydration, changes to meal size, and slower titration may help with these effects

GLP-1 receptor is expressed in human stomach mucosa: analysis of its cellular association and distribution within gastric glands

Vitamin B-12 shots are prescribed to treat vitamin B-12 deficiencies

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Persistent vomiting that doesn't improve with dose adjustment or dietary changes warrants a conversation with the prescribing doctor about whether to continue at the current dose