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therefore, pan-coronavirus vaccines would need to target epitopes that can inhibit binding to all coronavirus entry receptors

The 2016 approval for the treatment of ROS1 -positive metastatic NSCLC was based on a multicenter, prospective, single-arm trial enrolling 50 patients whose tumors were determined to be ROS1 -positive by fluorescence in situ hybridization (FISH) (96%) or reverse transcription polymerase chain reaction (RT-PCR) (4%) assays

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Abdominal fat loss, as well as sustained reductions of fasting insulin levels and markers of IR, have also been shown in patients with T2D and individuals with overweight/obesity and/or prediabetes after their administration [5860]

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