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A new study published in Science Translational Medicine last month showed that a molecule produced in the hindbrain by glial cells, octadecaneuropeptide (ODN), could suppress appetite, induce weight loss, and improve the regulation of glucose in the body in obese rodent models without the gastrointestinal side effects

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These are almost all positive things for the treatment of diabetes and obesity, which makes the glucagon signaling pathway an attractive target for an anti-obesity medication despite the induction of glucose production, but only if its hyperglycemic liability can be restrained

Its almost the same