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Another explanation for the decrease in punctuate NCOA4 staining is that while NCOA4 might be located in synapses in a control setting, and these synapses are lost in AD [45]

To evaluate the effect of CI inhibition on growth, organoids were seeded as fragments in Matrigel and treated the following day with water (CTRL), 5 M 5FU, 3 mM metformin or a combination of 5FU and metformin for 72 h

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patient uptake as coverage and access barriers decrease