Key Takeaways GLP-1 medications can slow digestion, which may contribute to constipation, bloating, cramping, and other GI symptoms
Avoid dose escalation while GI AEs persist
Both GLP-1 medications and bariatric surgery can reduce overall food intake, making hydration, protein intake, and supplementation more important
Other entero-pancreatic hormones and combination of entero-pancreatic hormones in the management of obesity Numerous entero-pancreatic hormones [GIP, glucagon, amylin and peptide YY (PYY) agonists and GIP antagonists] with diverse metabolic actions are currently under investigation either alone or in combination with GLP-1 RA (Fig
Once the peptides are reconstituted (mixed with bacteriostatic water), they must be stored in the fridge to maintain stability
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