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It is not yet FDA-approved but has shown remarkable weight loss results in phase 2 trials, with participants losing up to 24.2% of body weight at the highest dose over 48 weeks
The longer food takes to digest, the slower the gastric emptying which can exacerbate any adverse gastrointestinal effects
N Engl J Med (2015) 373:224757
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How Long Do Patients Stay on Contrave Before Reassessing
He showed that when normal rabbits were given oral glucose that their blood glucose rapidly returned to normal if given secretin extracts either by subcutaneous injection or by mouth
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