cagrilintide phase 2 Updates in Medicine | 🔬 REDEFINE 2: CagriSema in T2D + Obesity Original article link in bio 👥 3a RCT in 1206 adults with T2D (BMI ≥27, HbA1c 7–10%) 💉 Cagrilintide - Wikipedia

A deficiency in B12 can lead to megaloblastic anemia, characterized by larger-than-normal red blood cells that may not function properly

Fatigue combined with cold intolerance and brain fog warrants measuring Free T3 rather than TSH alone. The obese trial cohorts lost roughly 8% of body weight at 1 mg in Phase 2 and about 28% at 12 mg in the 80-week Phase 3 trial

Quality Indicators Third-party testing with published Certificates of Analysis (COA) provides the most reliable quality assurance

C max was analysed using the same approach, whereas t max and all exploratory pharmacokinetic endpoints were summarised by renal function group using descriptive statistics

Forward-looking statements are based on the current expectations, estimates, assumptions, and beliefs of management as of the date the relevant statement is made and are necessarily subject to a number of risks, uncertainties, and other factors

The drug is indicated for chronic weight management in patients with a body mass index (BMI) of 27 kg/m2 or greater who have at least one weight-related ailment or in patients with a BMI of 30 kg/m2 or greater