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The peptide reduces not only tumor growth, but also delivery and spread to distant tissues

Emodin and aloe-emodin are isomers with inhibitory effects on CYP1B1 activity (Shen et al., 2022)

Future research should employ advanced methodologies such as systems biology, single-cell transcriptomics, spatial omics, and high-resolution imaging to map the regulatory landscape of tophus formation with greater precision

Consequently, biomarker endpoints in studies of natural products must be rigorously standardized and critically evaluated

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A first important achievement of our study was the establishment of a novel mouse model based on the intraperitoneal injection of endometriotic human tissue in SCID mice