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Chaudhuri A, Ghanim H, Vora M, et al

A randomized controlled trial of liraglutide versus insulin detemir plus sitagliptin: Effective switch from intensive insulin therapy to the once-daily injection in patients with well-controlled type 2 diabetes

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However, despite low intra-portal insulin levels, low IGF-I and increased fat mass and decreased lean body mass, their glucose tolerance and insulin sensitivity remains unaffected and in fact, is comparable to normal controls (151, 152)

Iron, copper, zinc, and manganese are cofactors for the antioxidant enzymes catalase and superoxide dismutase, as shown below