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Benefit strategies must support these transitions by helping employees manage appetite changes, maintain eating structure, and sustain progress even as medication use evolves

86 The inhibition of 15-PGDH rejuvenates aged muscle by increasing autophagy and stem cell activity, 87 whereas Sestrins integrate stress and nutrient signals to prevent atrophy

doi: 10.1038/s41420-024-01891-x 264 WangY.LuoJ.LiS

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However, these methods may not be sufficient for individuals with significantly depleted levels