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Health Risks from Excessive Intake Vitamin B12 is a water-soluble vitamin, meaning excess amounts are typically excreted in urine, and toxicity is considered very low

Individuals with certain genetic predispositionssuch as variants in methionine synthase (MTHFR) and cobalamin metabolism pathwaysmay respond more distinctly to B vitamin protocols

10.1523/eneuro.0151-17.2017 114 StaszewskiR

In the United States, patients usually receive vitamin B 12 injections of 1 mg/d in their first week of treatment

Injections deliver 100% of the dose straight into your bloodstream

After removing duplicates, UniProt standardized entries were used to identify drug-relevant targets