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Higher concentrations deliver more peptide per application but are not always proportionally more effective, since the skins capacity to take up and respond to the peptide has limits

In some cases, some vomiting or other GI issues might occur

The SURMOUNT trials in patients without diabetes showed even greater weight loss, with the 15 mg dose producing an average loss of 20.9 percent of body weight at 72 weeks compared to 14.9 percent for semaglutide in similar populations

Along with quick fat loss and looser skin, nutritional deficiencies may also play a role, especially if weight loss isnt paired with proper micronutrient intake, says Nayan Patel, PharmD, founder of Auro Wellness and Auro Skincare