Clinical trial data show that while fat mass accounts for the majority of weight loss, some lean mass reduction also occurs, which could potentially affect muscle function

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Engaging in foot exercises and stretching routines can strengthen muscles and improve flexibility
In a clinical trial, pure genistein supplementation (54 mg/day, P.O for one year) improved both cardiac function and left atrial remodeling in postmenopausal women with metabolic syndrome [138]
doi:10.1016/s0142-9612(03)00331-4 131
Thus, micronutrient supplementation, especially in individuals with overt or marginal deficiencies, could possibly improve overall mood state and psychological well-being